一氧化氮NO荧光探针DAF-2 DA CAS 205391-02-2

	货号	16294	存储条件	在零下15度以下保存, 避免光照
	规格	1 mg	价格	3732
	Ex (nm)		Em (nm)
	分子量	446.42	溶剂	DMSO
	产品详细介绍

简要概述

产品基本信息

货号：16294

产品名称：一氧化氮NO荧光探针DAF-2 DA

CAS：205391-02-2

规格：1mg

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

分子量：446.42

溶剂：DMSO

产品介绍

DAF-2双乙酸盐是DAF-2的细胞可渗透性的版本，DAF-2是一氧化氮（NO）的检测和生物成像的灵敏荧光指示剂。进入细胞后，DAF-2双乙酸酯会被细胞酯酶水解为细胞渗透性较低的DAF-2，从而防止了DAF-2双乙酸酯从细胞中泄漏造成的信号损失。在氧气存在下，DAF-2与NO反应生成高度荧光的三唑荧光素。可以使用标准FITC过滤器组轻松检测细胞内荧光（由DAF-2双乙酸酯生成）。DAF-2双乙酸盐可用于在内皮细胞中产生少量NO的细胞以及在巨噬细胞中产生大量NO的细胞。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的一氧化氮NO荧光探针DAF-2 DA。 

参考文献

Does Melatonin Exert Its Effect on Ram Sperm Capacitation Through Nitric Oxide Synthase Regulation?
Authors: Miguel-Jiménez, Sara and Carvajal-Serna, Melissa and Calvo, Silvia and Casao, Adriana and Cebrián-Pérez, José Álvaro and Muiño-Blanco, Teresa and Pérez-Pe, Rosaura
Journal: International journal of molecular sciences (2020)

Involvement of nitrate reductase-dependent nitric oxide production in magnetopriming-induced salt tolerance in soybean.
Authors: Kataria, Sunita and Jain, Meeta and Tripathi, Durgesh K and Singh, Vijay P
Journal: Physiologia plantarum (2020): 422-436

Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function.
Authors: Lan, Cong and Chen, Xinjian and Zhang, Yuxun and Wang, Wei and Wang, Wei Eric and Liu, Yukai and Cai, Yue and Ren, Hongmei and Zheng, Shuo and Zhou, Lin and Zeng, Chunyu
Journal: BMC cardiovascular disorders (2018): 43

Nitric oxide in frozen-thawed equine sperm: Effects on motility, membrane integrity and sperm capacitation.
Authors: de Andrade, André F C and Arruda, Rubens P and Torres, Mariana A and Pieri, Naira C G and Leite, Ticiano G and Celeghini, Eneiva Carla C and Oliveira, Leticia Z and Gardés, Thayna P and Bussiere, Maria Clara C and Silva, Daniela F
Journal: Animal reproduction science (2018): 176-184

Inhibition of endothelial nitric oxide synthase decreases breast cancer cell MDA-MB-231 adhesion to intact microvessels under physiological flows.
Authors: Zhang, Lin and Zeng, Min and Fu, Bingmei M
Journal: American journal of physiology. Heart and circulatory physiology (2016): H1735-47

Inhibition of autophagy by chloroquine stimulates nitric oxide production and protects endothelial function during serum deprivation.
Authors: Pestana, Cezar Rangel and Oishi, Jorge Camargo and Salistre-Araújo, Heloísa Sobreiro and Rodrigues, Gerson Jhonatan
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2015): 1168-77

Oxidative Stress-Dependent Coronary Endothelial Dysfunction in Obese Mice.
Authors: Gamez-Mendez, Ana María and Vargas-Robles, Hilda and Ríos, Amelia and Escalante, Bruno
Journal: PloS one (2015): e0138609

Traumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of function.
Authors: Villalba, Nuria and Sonkusare, Swapnil K and Longden, Thomas A and Tran, Tram L and Sackheim, Adrian M and Nelson, Mark T and Wellman, George C and Freeman, Kalev
Journal: Journal of the American Heart Association (2014): e001474

Generation and characterization of a spontaneously immortalized endothelial cell line from mice microcirculation.
Authors: Loiola, Rodrigo A and Torres, Tathiany C and Aburaya, Carla M and Landgraf, Maristella A and Landgraf, Richardt G and Bosco Pesquero, João and Fernandes, Liliam
Journal: Experimental cell research (2013): 1102-10

Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones.
Authors: Mondal, Debasis and Liu, Kai and Hamblin, Milton and Lasky, Joseph A and Agrawal, Krishna C
Journal: The Ochsner journal (2013): 76-90

一氧化氮NO荧光探针DAF-FM双乙酸盐 CAS 254109-22-3

	货号	16298	存储条件	在零下15度以下保存, 避免光照
	规格	10×50 ug	价格	2472
	Ex (nm)		Em (nm)
	分子量	496.42	溶剂	DMSO
	产品详细介绍

简要概述

产品基本信息

货号：16298

产品名称：一氧化氮NO荧光探针DAF-FM双乙酸盐

CAS：254109-22-3

规格：10x50ug

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

分子量：496.42

溶剂：DMSO

产品介绍

DAF-FM 双乙酸盐是DAF-FM的一种细胞渗透性更高的版本，DAF-FM是一氧化氮（NO）的检测和生物成像的敏感荧光指示剂。进入细胞后，DAF-FM双乙酸酯会被细胞酯酶水解为细胞渗透性较低的DAF-FM，从而防止了DAF-FM双乙酸酯从细胞中渗出引起的信号损失。在氧气存在下，DAF-FM与NO反应生成高度荧光的二氟-三唑并荧光素。可以使用标准FITC滤波器组轻松检测细胞内荧光（由DAF-FM二乙酸酯生成）。DAF-FM二乙酸盐可在细胞中用于广泛的NO产生，例如少量的NO产生（例如在内皮细胞中）和大量的NO产生（例如在巨噬细胞中）。与DAF-2 DA相比，DAF-FM双乙酸盐是用于检测NO的更加灵敏且光稳定的荧光探针。此外，DAF-FM对pH的敏感性比DAF-2低得多。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的一氧化氮NO荧光探针DAF-FM双乙酸盐。 

参考文献

A reliable fluorimetric method to screen the nitric oxide synthase inhibitors in 96 well plate.
Authors: Agrawal, Saurabh and Kumari, Rita and Luthra, Pratibha Mehta
Journal: Analytical biochemistry (2019): 42-44

Modification of endoplasmic reticulum Ca2+ stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease.
Authors: Huang, Hsueh-Meei and Chen, Huan-Lian and Xu, Hui and Gibson, Gary E
Journal: Free radical biology & medicine (2005): 979-89

一氧化氮NO荧光探针DAF-2 CAS 205391-01-1

	货号	16290	存储条件	在零下15度以下保存, 避免光照
	规格	1 mg	价格	3732
	Ex (nm)		Em (nm)
	分子量	362.34	溶剂	DMSO
	产品详细介绍

简要概述

产品基本信息

货号：16290

产品名称：一氧化氮NO荧光探针DAF-2

CAS：205391-01-1

规格：1mg

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

分子量：362.34

溶剂：DMSO

产品介绍

弱荧光DAF-2是一种敏感的荧光指示剂，通常用于检测一氧化氮（NO）。它在氧气存在下与NO反应生成高度荧光的荧光素。可以使用标准FITC滤光片组检测其荧光。在中性pH值下，NO的检出限为2-5 nM。它能用于实时NO检测，但是必须通过实验确定最佳DAF-2浓度才能进行细胞NO检测。例如，通过从测得的总荧光中减去DAF-2自发荧光，可将低DAF-2浓度（例如0.1μM）用于内皮细胞一氧化氮的实时检测。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的一氧化氮NO荧光探针DAF-2。 

参考文献

Does Melatonin Exert Its Effect on Ram Sperm Capacitation Through Nitric Oxide Synthase Regulation?
Authors: Miguel-Jiménez, Sara and Carvajal-Serna, Melissa and Calvo, Silvia and Casao, Adriana and Cebrián-Pérez, José Álvaro and Muiño-Blanco, Teresa and Pérez-Pe, Rosaura
Journal: International journal of molecular sciences (2020)

Involvement of nitrate reductase-dependent nitric oxide production in magnetopriming-induced salt tolerance in soybean.
Authors: Kataria, Sunita and Jain, Meeta and Tripathi, Durgesh K and Singh, Vijay P
Journal: Physiologia plantarum (2020): 422-436

Exercise training improves vascular reactivity in ovariectomized rats subjected to myocardial infarction.
Authors: de Oliveira, Suelen Guedes and Claudio, Erick Roberto Gonçalves and de Almeida, Simone Alves and Mengal, Vinicius and da Silva, Fabricio Bragança and Silva, Nyam Florêncio and Mauad, Helder and de Abreu, Glaucia Rodrigues
Journal: PloS one (2019): e0215568

Extracellular and Intracellular NO Detection in Plants by Diaminofluoresceins.
Authors: Silveira, Neidiquele Maria and Machado, Eduardo Caruso and Ribeiro, Rafael Vasconcelos
Journal: Methods in molecular biology (Clifton, N.J.) (2019): 103-108

Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function.
Authors: Lan, Cong and Chen, Xinjian and Zhang, Yuxun and Wang, Wei and Wang, Wei Eric and Liu, Yukai and Cai, Yue and Ren, Hongmei and Zheng, Shuo and Zhou, Lin and Zeng, Chunyu
Journal: BMC cardiovascular disorders (2018): 43

Inter- and intra-subject variability of nitric oxide levels in leukocyte subpopulations.
Authors: Maharaj, Sheena and Lu, Kim D and Radom-Aizik, Shlomit and Zaldivar, Frank and Haddad, Fadia and Shin, Hye-Won and Leu, Szu-Yun and Nussbaum, Eliezer and Randhawa, Inderpal and Cooper, Dan M
Journal: Nitric oxide : biology and chemistry (2018): 41-45

Nandrolone combined with strenuous resistance training reduces vascular nitric oxide bioavailability and impairs endothelium-dependent vasodilation.
Authors: Guzzoni, Vinicius and Cunha, Tatiana Sousa and das Neves, Vander José and Briet, Larissa and Costa, Rafaela and Moura, Maria José Costa Sampaio and Oliveira, Vanessa and Franco, Maria do Carmo Pinho and Novaes, Pedro Duarte and Marcondes, Fernanda Klein
Journal: Steroids (2018): 7-13

Nitric oxide in frozen-thawed equine sperm: Effects on motility, membrane integrity and sperm capacitation.
Authors: de Andrade, André F C and Arruda, Rubens P and Torres, Mariana A and Pieri, Naira C G and Leite, Ticiano G and Celeghini, Eneiva Carla C and Oliveira, Leticia Z and Gardés, Thayna P and Bussiere, Maria Clara C and Silva, Daniela F
Journal: Animal reproduction science (2018): 176-184

Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway.
Authors: Donato, Verónica and Ayala, Facundo Rodríguez and Cogliati, Sebastián and Bauman, Carlos and Costa, Juan Gabriel and Leñini, Cecilia and Grau, Roberto
Journal: Nature communications (2017): 14332

Chronic iron overload induces functional and structural vascular changes in small resistance arteries via NADPH oxidase-dependent O2- production.
Authors: Ribeiro Júnior, Rogério Faustino and Marques, Vinicius Bermond and Nunes, Dieli Oliveira and Stefanon, Ivanita and Dos Santos, Leonardo
Journal: Toxicology letters (2017): 43-52

一氧化氮NO荧光探针DAF-2 DA CAS 205391-02-2

	货号	16293	存储条件	在零下15度以下保存, 避免光照
	规格	10×50 ug	价格	2472
	Ex (nm)		Em (nm)
	分子量	446.42	溶剂	DMSO
	产品详细介绍

简要概述

产品基本信息

货号：16293

产品名称：一氧化氮NO荧光探针DAF-2 DA

CAS：205391-02-2

规格：10x50ug

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

分子量：446.42

溶剂：DMSO

产品介绍

DAF-2双乙酸盐是DAF-2的细胞可渗透性的版本，DAF-2是一氧化氮（NO）的检测和生物成像的灵敏荧光指示剂。进入细胞后，DAF-2双乙酸酯会被细胞酯酶水解为细胞渗透性较低的DAF-2，从而防止了DAF-2双乙酸酯从细胞中泄漏造成的信号损失。在氧气存在下，DAF-2与NO反应生成高度荧光的三唑荧光素。可以使用标准FITC过滤器组轻松检测细胞内荧光（由DAF-2双乙酸酯生成）。DAF-2双乙酸盐可用于在内皮细胞中产生少量NO的细胞以及在巨噬细胞中产生大量NO的细胞。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的一氧化氮NO荧光探针DAF-2 DA。 

参考文献

Does Melatonin Exert Its Effect on Ram Sperm Capacitation Through Nitric Oxide Synthase Regulation?
Authors: Miguel-Jiménez, Sara and Carvajal-Serna, Melissa and Calvo, Silvia and Casao, Adriana and Cebrián-Pérez, José Álvaro and Muiño-Blanco, Teresa and Pérez-Pe, Rosaura
Journal: International journal of molecular sciences (2020)

Involvement of nitrate reductase-dependent nitric oxide production in magnetopriming-induced salt tolerance in soybean.
Authors: Kataria, Sunita and Jain, Meeta and Tripathi, Durgesh K and Singh, Vijay P
Journal: Physiologia plantarum (2020): 422-436

Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function.
Authors: Lan, Cong and Chen, Xinjian and Zhang, Yuxun and Wang, Wei and Wang, Wei Eric and Liu, Yukai and Cai, Yue and Ren, Hongmei and Zheng, Shuo and Zhou, Lin and Zeng, Chunyu
Journal: BMC cardiovascular disorders (2018): 43

Nitric oxide in frozen-thawed equine sperm: Effects on motility, membrane integrity and sperm capacitation.
Authors: de Andrade, André F C and Arruda, Rubens P and Torres, Mariana A and Pieri, Naira C G and Leite, Ticiano G and Celeghini, Eneiva Carla C and Oliveira, Leticia Z and Gardés, Thayna P and Bussiere, Maria Clara C and Silva, Daniela F
Journal: Animal reproduction science (2018): 176-184

Inhibition of endothelial nitric oxide synthase decreases breast cancer cell MDA-MB-231 adhesion to intact microvessels under physiological flows.
Authors: Zhang, Lin and Zeng, Min and Fu, Bingmei M
Journal: American journal of physiology. Heart and circulatory physiology (2016): H1735-47

Inhibition of autophagy by chloroquine stimulates nitric oxide production and protects endothelial function during serum deprivation.
Authors: Pestana, Cezar Rangel and Oishi, Jorge Camargo and Salistre-Araújo, Heloísa Sobreiro and Rodrigues, Gerson Jhonatan
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2015): 1168-77

Oxidative Stress-Dependent Coronary Endothelial Dysfunction in Obese Mice.
Authors: Gamez-Mendez, Ana María and Vargas-Robles, Hilda and Ríos, Amelia and Escalante, Bruno
Journal: PloS one (2015): e0138609

Traumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of function.
Authors: Villalba, Nuria and Sonkusare, Swapnil K and Longden, Thomas A and Tran, Tram L and Sackheim, Adrian M and Nelson, Mark T and Wellman, George C and Freeman, Kalev
Journal: Journal of the American Heart Association (2014): e001474

Generation and characterization of a spontaneously immortalized endothelial cell line from mice microcirculation.
Authors: Loiola, Rodrigo A and Torres, Tathiany C and Aburaya, Carla M and Landgraf, Maristella A and Landgraf, Richardt G and Bosco Pesquero, João and Fernandes, Liliam
Journal: Experimental cell research (2013): 1102-10

Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones.
Authors: Mondal, Debasis and Liu, Kai and Hamblin, Milton and Lasky, Joseph A and Agrawal, Krishna C
Journal: The Ochsner journal (2013): 76-90

一氧化氮NO荧光探针DAF-FM CAS 254109-20-1

	货号	16296	存储条件	在零下15度以下保存, 避免光照
	规格	1 mg	价格	3732
	Ex (nm)		Em (nm)
	分子量	412.35	溶剂	DMSO
	产品详细介绍

简要概述

产品基本信息

货号：16296

产品名称：一氧化氮NO荧光探针DAF-FM

CAS：254109-20-1

规格：1mg

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

分子量：412.35

溶剂：DMSO

产品介绍

DAF-2被广泛用于检测细胞中的一氧化氮（NO）。DAF-FM是DAF的改进版本。与DAF-2相比，DAF-FM是用于检测NO的更加灵敏且光稳定性更高的荧光探针。此外，DAF-FM对pH的敏感性比DAF-2低得多。DAF-FM不能像双乙酸酯衍生物DAF-DA那样具有细胞渗透性，但是它不需要被胞质酶激活。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的一氧化氮NO荧光探针DAF-FM。 

参考文献

Association between expression of AMPK pathway and adiponectin, leptin, and vascular endothelial function in rats with coronary heart disease.
Authors: Li, J-M and Lu, W and Ye, J and Han, Y and Chen, H and Wang, L-S
Journal: European review for medical and pharmacological sciences (2020): 905-914

Histamine induces intracellular Ca2+ oscillations and nitric oxide release in endothelial cells from brain microvascular circulation.
Authors: Berra-Romani, Roberto and Faris, Pawan and Pellavio, Giorgia and Orgiu, Matteo and Negri, Sharon and Forcaia, Greta and Var-Gaz-Guadarrama, Verónica and Garcia-Carrasco, Mario and Botta, Laura and Sancini, Giulio and Laforenza, Umberto and Moccia, Francesco
Journal: Journal of cellular physiology (2020): 1515-1530

Methods for Measuring Nitrate Reductase, Nitrite Levels, and Nitric Oxide from Plant Tissues.
Authors: Wany, Aakanksha and Pathak, Pradeep Kumar and Gupta, Kapuganti Jagadis
Journal: Methods in molecular biology (Clifton, N.J.) (2020): 15-26

Nitric oxide restores peripheral blood mononuclear cell adhesion against hypoxia via NO-cGMP signalling.
Authors: Behera, Jyotirmaya and Nagarajan, Shunmugam and Saran, Uttara and Kumar, Ravi and Keshri, Gaurav K and Suryakumar, Geetha and Chatterjee, Suvro
Journal: Cell biochemistry and function (2020)

Nitro-Oleic Acid in Seeds and Differently Developed Seedlings of Brassica napus L.
Authors: Vollár, Martin and Feigl, Gábor and Oláh, Dóra and Horváth, Attila and Molnár, Árpád and Kúsz, Norbert and Ördög, Attila and Csupor, Dezső and Kolbert, Zsuzsanna
Journal: Plants (Basel, Switzerland) (2020)

Omentin-1 protects against high glucose-induced endothelial dysfunction via the AMPK/PPARδ signaling pathway.
Authors: Liu, Fang and Fang, Shaohong and Liu, Xinxin and Li, Ji and Wang, Xuedong and Cui, Jinjin and Chen, Tao and Li, Zhaoying and Yang, Fan and Tian, Jiangtian and Li, Hulun and Yin, Li and Yu, Bo
Journal: Biochemical pharmacology (2020): 113830

7-Keto-Cholesterol and Cholestan-3beta, 5alpha, 6beta-Triol Induce Eryptosis through Distinct Pathways Leading to NADPH Oxidase and Nitric Oxide Synthase Activation.
Authors: Attanzio, Alessandro and Frazzitta, Anna and Cilla, Antonio and Livrea, Maria A and Tesoriere, Luisa and Allegra, Mario
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2019): 933-947

A reliable fluorimetric method to screen the nitric oxide synthase inhibitors in 96 well plate.
Authors: Agrawal, Saurabh and Kumari, Rita and Luthra, Pratibha Mehta
Journal: Analytical biochemistry (2019): 42-44

Acute spatial spread of NO-mediated potentiation during hindpaw ischaemia in mice.
Authors: Onishi, Takeshi and Watanabe, Tatsunori and Sasaki, Mika and Kamiya, Yoshinori and Horie, Masao and Tsukano, Hiroaki and Hishida, Ryuichi and Kohno, Tatsuro and Takebayashi, Hirohide and Baba, Hiroshi and Shibuki, Katsuei
Journal: The Journal of physiology (2019): 3441-3455

Androgens drive microvascular endothelial dysfunction in women with polycystic ovary syndrome: role of the endothelin B receptor.
Authors: Usselman, Charlotte W and Yarovinsky, Timur O and Steele, Frances E and Leone, Cheryl A and Taylor, Hugh S and Bender, Jeffrey R and Stachenfeld, Nina S
Journal: The Journal of physiology (2019): 2853-2865