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荧光素醛[5-FAM醛]
![荧光素醛[5-FAM醛] 货号9000](http://www.gewhatman.cn/wp-content/uploads/2022/05/20220508_62773f0bca15b.svg) |
货号 | 9000 | 存储条件 | 在零下15度以下保存, 避免光照 |
| 规格 | 5 mg | 价格 | 3732 | |
| Ex (nm) | 493 | Em (nm) | 517 | |
| 分子量 | 550.52 | 溶剂 | DMSO | |
| 产品详细介绍 | ||||
简要概述
产品基本信息
货号：9000
产品名称：荧光素醛[5-FAM醛]
规格：5 mg
储存条件：-15℃避光防潮
保质期：24个月
产品物理化学光谱特性
分子量：445.43
溶剂：DMSO
激发波长(nm)：493
发射波长(nm)：517
消光系数（cm-1 M-1）:83000
校正因子（260nm）:0.32
校正因子 (280 nm)：0.178
产品介绍
荧光素醛是可以与胺，肼或羟胺反应的反应性荧光染料。荧光素是使用最广泛的绿色荧光染料。醛基可与pH 5-9的胺，酰肼或羟胺基反应。与胺反应性琥珀酰亚胺基酯基（NHS）不同，醛可以在酸性pH下与N端胺基反应，这是某些生物缀合反应有时需要的条件。醛与胺基反应形成席夫碱（Schiff base）。用氢化物进一步还原将形成稳定的C-N键。醛与其他基团之间的反应可实现荧光素染料的位点特异性缀合和标记，使其靶向分子上的所需位置。共轭荧光素染料可以很容易地通过普通的荧光仪器在FITC通道下检测到。
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参考文献
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Journal: ChemPlusChem (2020): 1164-1170
Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization.
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Journal: Toxicology and applied pharmacology (2020): 114982
Bisretinoid phospholipid and vitamin A aldehyde: Shining a light.
Authors: Kim, Hye Jin and Sparrow, Janet R
Journal: Journal of lipid research (2020)
Characterization of ascites-derived aldehyde dehydrogenase-positive ovarian cancer stem cells isolated from Leghorn chickens.
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Journal: Poultry science (2020): 2203-2214
Citral Inhibition of Human Salivary Aldehyde Dehydrogenase.
Authors: Laskar, Amaj Ahmed and Khan, Masood Alam and Ahmad, Sumbul and Hashmi, Amiruddin and Younus, Hina
Journal: Cell biochemistry and biophysics (2020): 31-42
Didactic approach recounting advances and limitations in novel glutathione and cysteine detection (reduced GSH probe) with mixed coumarin, aldehyde, and phenyl-selenium chemistry.
Authors: Lee, Woohyun and Mulay, Sandip V and Shimodaira, Shingo and Abdillah, Ariq and Palma, Jaymee and Kim, Youngsam and Yudhistira, Tesla and Churchill, David G
Journal: Methods in enzymology (2020): 267-289
Establishing sample-preparation protocols for X-ray phase-contrast CT of rodent spinal cords: Aldehyde fixations and osmium impregnation.
Authors: Barbone, Giacomo E and Bravin, Alberto and Mittone, Alberto and Kraiger, Markus J and Hrabě de Angelis, Martin and Bossi, Mario and Ballarini, Elisa and Rodriguez-Menendez, Virginia and Ceresa, Cecilia and Cavaletti, Guido and Coan, Paola
Journal: Journal of neuroscience methods (2020): 108744
Introduction of an Aldehyde Handle on Nanobodies by Affinity-Guided Labeling.
Authors: Mortensen, Michael R and Skovsgaard, Mikkel B and Märcher, Anders and Andersen, Veronica L and Palmfeldt, Johan and Nielsen, Thorbjørn B and Tørring, Thomas and Laursen, Nick S and Andersen, Kasper R and Kjems, Jørgen and Gothelf, Kurt V
Journal: Bioconjugate chemistry (2020): 1295-1300
Isocyanoacetate-Aldehyde Polymerization: A Facile Tool toward Functional Oxazoline-Containing Polymers.
Authors: Cheng, Tianyu and Chen, Yizhao and Ding, Jie and Qin, Anjun and Tang, Ben Zhong
Journal: Macromolecular rapid communications (2020): e2000179
Preparation and optical parameter characterization of two aldehyde derivative thin films for photonic applications by drop casting method.
Authors: Melavanki, Raveendra and Vaijayanthimala, S and Yallur, Basappa Chanabasappa and Shelar, Vikas M and Singh, Diksha and Sadasivuni, Kishor Kumar and Patil, N R
Journal: Luminescence : the journal of biological and chemical luminescence (2020): 903-912
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