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钙离子荧光探针Quin-2, AM CAS 83104-85-2
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货号 | 21050 | 存储条件 | 在零下15度以下保存, 避免光照 |
| 规格 | 1 mg | 价格 | 2328 | |
| Ex (nm) | 353 | Em (nm) | 495 | |
| 分子量 | 829.76 | 溶剂 | DMSO | |
| 产品详细介绍 | ||||
简要概述
产品基本信息
货号：21050
产品名称：钙离子荧光探针Quin-2, AM
CAS：83104-85-2
规格：1mg
储存条件：-15℃避光防潮
保质期：24个月
产品物理化学光谱特性
分子量：829.76
溶剂：DMSO
激发波长(nm)：353
发射波长(nm)：495
适用仪器
| 荧光酶标仪 | |
| 激发： | 340nm |
| 发射： | 495nm |
| cutoff: | 475nm |
| 推荐孔板： | 黑色透明 |
| 读取模式： | 底读模式 |
产品介绍
钙离子荧光探针Quin-2, AM是美国AAT Bioquest生产的钙离子荧光探针，Quin-2与钙紧密结合，与钙螯合剂EGTA类似，与钙的结合能力比镁更紧密。钙的结合会导致紫外线吸收和荧光发生很大变化。钙结合时引起荧光的光的波长比不结合时引起荧光的光的波长长。当在两个不同的波长下激发时，在两个波长下的荧光强度之比即为与游离钙结合的浓度之比。可以精确测量游离Quin-2的浓度，因此可以精确计算出游离钙的浓度。可以将Quin-2注射到细胞中以测量细胞内钙浓度的瞬时变化。Quin-2 AM对细胞具有渗透性，并用于研究活细胞。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的钙离子荧光探针Quin-2, AM。
点击查看实验方案
钙离子篇：时间轴式讲解应用于钙离子检测的探针
参考文献
W-5 and quin 2-AM reverse the inhibitory effect of insulin on lipolysis due to dibutyryl cAMP
Authors: Goko H, Matsuoka A.
Journal: Diabetes Res Clin Pract (1999): 101
Calcium chelator Quin-2 prevents crocidolite-induced DNA strand breakage in human white blood cells
Authors: Faux SP, Michelangeli F, Levy LS.
Journal: Mutat Res (1994): 209
Fluorescence lifetime imaging of intracellular calcium in COS cells using Quin-2
Authors: Lakowicz JR, Szmacinski H, Nowaczyk K, Lederer WJ, Kirby MS, Johnson ML.
Journal: Cell Calcium (1994): 7
Possible mechanisms of epinephrine actions in quin-2-loaded platelets refractory to arachidonic acid
Authors: Rao GH, Gerrard JM, Murthy M, White JG.
Journal: Biochem Med Metab Biol (1993): 322
Fluorescence lifetime imaging of calcium using Quin-2
Authors: Lakowicz JR, Szmacinski H, Nowaczyk K, Johnson ML.
Journal: Cell Calcium (1992): 131
Involvement of calcium and iron in Quin 2 toxicity to isolated hepatocytes
Authors: Carpenter-Deyo L, Reed DJ.
Journal: J Pharmacol Exp Ther (1991): 747
Toxicity to isolated hepatocytes caused by the intracellular calcium indicator, Quin 2
Authors: Carpenter-Deyo L, Duimstra JR, Hedstrom O, Reed DJ.
Journal: J Pharmacol Exp Ther (1991): 739
Aspirin, prostaglandin E1 and Quin-2 AM-induced platelet dysfunction: restoration of function by noradrenalin
Authors: Rao GH, White JG.
Journal: Prostaglandins Leukot Essent Fatty Acids (1990): 141
Characterization of indo-1 and quin-2 as spectroscopic probes for Zn2(+)-protein interactions
Authors: Jefferson JR, Hunt JB, Ginsburg A.
Journal: Anal Biochem (1990): 328
Effect of Quin-2 on Ca2+ uptake mediated by Na+i/Ca2+o exchange and 45Ca2+ efflux in rat brain synaptosomes: a requirement for [Ca2+]i
Authors: Blanco P, Martinez-Serrano A, Bogonez E, Satrustegui J.
Journal: Cell Calcium (1990): 25